Arbidol Re-included in the New Edition of the COVID-19 Diagnosis and Treatment Protocol


发布时间:2020-08-20

【概要描述】 On August 19, the National Health Commission and the State Administration of Traditional Chinese Medicine issued the “Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (Trial Version 8).” In this latest version of the protocol, arbidol has once again been included as an antiviral treatment.

 

 


Previously, the team led by Li Lanjuan, an academician of the Chinese Academy of Engineering and a member of the National Health Commission’s High-Level Expert Group, announced in Wuhan their latest research findings on the treatment of pneumonia caused by novel coronavirus infection, which confirmed the clinical efficacy of arbidol. On February 19, arbidol was included for the first time in the Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (Trial Version 6). On March 4, arbidol was once again incorporated into the Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (Trial Version 7).
According to available information, Arbidol is an antiviral agent primarily indicated for the treatment of upper respiratory tract infections caused by influenza A and B viruses, among others, and exhibits broad-spectrum antiviral activity. Its mechanism of action involves inhibiting the fusion of the viral envelope with host cell membranes, thereby blocking the initial step of viral entry. In addition, Arbidol can induce the production of endogenous interferon, which not only suppresses viral replication but also modulates and enhances the host’s immune response, conferring multiple mechanisms of antiviral efficacy. In 2019, it was included in the National Health Commission’s list of clinically recommended antiviral agents for influenza.
Shijiazhuang Sihua Pharmaceutical is one of the earliest domestic pharmaceutical companies to develop arbidol, and its arbidol hydrochloride capsules have played a positive role in COVID-19 prevention and control since the outbreak began, being included on the drug reserve lists for COVID-19 prevention and control in numerous provinces and cities.
During the COVID-19 pandemic, Shijiazhuang No. 4 Pharmaceutical Co., Ltd. conscientiously fulfilled its social responsibility by making every effort to ensure the supply of Arbidol Hydrochloride Capsules, successfully completing both national allocation and provincial-level procurement and stockpiling tasks. The company received high praise from the Medical Supplies Guarantee Group of the Joint Prevention and Control Mechanism under the State Council for Responding to the Novel Coronavirus Pneumonia Epidemic, the Party Committee and Government of the Shennongjia Forestry District, as well as relevant medical institutions and pharmaceutical trading enterprises.
At present, the global COVID-19 pandemic continues to spread. In response to the evolving epidemic situation abroad, Shijiazhuang Sihua Pharmaceutical has stepped up to its social responsibility: while successfully ensuring the domestic supply of abidor hydrochloride capsules, the company has also mobilized production capacity to meet international market demand and support the global fight against the pandemic. To date, Shijiazhuang Sihua Pharmaceutical has reached export intentions for abidor hydrochloride capsules and other anti-pandemic drugs with more than 10 international clients, and some shipments have already been dispatched.

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